Research Reports
Computational Drug Design: Molecular Docking of Lopinavir with HIV-1 Protease
Nov 2021 · archived · Shanghai Foreign Language School Affiliated to SISU, Minhang Foreign Language School · Rui Zhang
A generated English portfolio report based on a high-school research project using Schrödinger Maestro to dock lopinavir with HIV-1 protease and compare grid settings through Glide GScore and interaction analysis.
- molecular docking
- HIV protease
- computational biology
- drug design
Summary
This report is a cleaned English portfolio artifact based on a Chinese high-school research report and presentation. The original work modelled the docking of lopinavir with HIV-1 protease using Schrödinger Maestro and compared docking outcomes under 15, 18, and 20 Å grid settings.
Context
The original project received First Prize in the 2021 Shanghai Youth Science and Innovation Workstation Competition. It is listed here as a project-report artifact, not as peer-reviewed biomedical research.
Notes on status
The report and Beamer deck are generated portfolio versions. They are intended to show modelling workflow, software exposure, and scientific interpretation while keeping the public claim appropriately bounded.